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82. Su, Z-M.; Zhu, J.; Poole, D. L.; Rafiee, M.; Paton, R. S.; Weix, D. J.; Stahl, S. S. Selective Ni-Catalyzed Cross-Electrophile Coupling of Heteroaryl Chlorides and Aryl Bromides at 1:1 Substrate Ratio J. Am. Chem. Soc. 2025, 147, 353–361
81. Young, S. H.; Andon, J. S.; Lim, J.; Franke, M. C.; Wang, T.; Weix, D.J.; Buller, A.R. Chemoenzymatic cascade synthesis of metal-chelating α-amino acids ChemCatChem 2024, e202401958
80. Ehehalt, L. E.†; Beleh, O. M.†; Priest, I. C.; Mouat, J. M.; Olszewski, A. K.; Ahern, B. N.; Cruz, A. R.; Chi, B. K.; Castro, A. J.; Kang, K.; Wang, J.; Weix, D. J. Cross-Electrophile Coupling: Principles, Methods, and Applications in Synthesis Chem. Rev. 2024, 124, 13397–13569
79. Cardinale, L.; Beutner, G. L.; Bemis, C. Y.; Weix, D. J.; Stahl, S. S. Non-Innocent Role of Sacrificial Anodes in Electrochemical Nickel-Catalyzed C(sp2)–C(sp3) Cross-Electrophile Coupling J. Am. Chem. Soc. 2024, 146, 32249–32254
78. Nsouli, R.; Nayah, S.†; Balakrishnan, V.†; Lin, J.-Y.†; Chi, B. K.; Ford, H. G.; Tran, A. V.; Guzei, I. A.; Basca, J.; Armada, N. R.; Zenov, F.; Weix, D. J.; Ackerman-Biegasiewicz, L. K. G. Decarboxylative Cross-Coupling Enabled by Fe and Ni Metallaphotoredox Catalysis J. Am. Chem. Soc. 2024, 146, 29551–29559
77. Huang, Z.; Akana, M. E.; Sanders, K. M.; Weix, D. J. A decarbonylative approach to alkylnickel intermediates and C(sp3)-C(sp3) bond formation Science 2024, 385, 1331-1337
76. Beleh, O. M.; Alomari, S.; Weix, D. J. Synthesis of Stereodefined Enones from the Cross-Electrophile Coupling of Activated Acrylic Acids with Alkyl Bromides Org. Lett. 2024, 26, 7217–7221
75. Chi, B. K.; Gavin, S. J.; Ahern, B. N.; Peperni, N.; Monfette, S.; Weix, D. J. Sulfone Electrophiles in Cross-Electrophile Coupling: Nickel-Catalyzed Difluoromethylation of Aryl Bromides ACS Catal. 2024, 14, 11087–11100
74. Weight, B. M.; Weix, D. J.; Tonzetich, Z. J.; Krauss, T. D.; Huo, P. Cavity Quantum Electrodynamics Enables para- and ortho-Selective Electrophilic Bromination of Nitrobenzene J. Am. Chem. Soc. 2024, 146, 16184–16193
73. Tcyrulnikov, S.; Hubbell, A. K.; Pedro, D.; Reyes, G. P.; Monfette, S.; Weix, D. J.; Hansen, E. C. Computationally Guided Ligand Discovery from Compound Libraries and Discovery of a New Class of Ligands for Ni-Catalyzed Cross-Electrophile Coupling of Challenging Quinoline Halides J. Am. Chem. Soc. 2024, 146, 6947–6954
72. Franke, M. C.; Weix. D. J. Recent Advances in Electrochemical, Ni-Catalyzed C−C Bond Formation. Isr. J. Chem. 2024, 64, e202300089
71. Akana, M. E.; Tcyrulnikov, S.; Akana-Schneider, B. D.; Reyes, G. P.; Monfette, S.; Sigman, M. S.; Hansen, E. C.; Weix, D. J. Computational Methods Enable the Prediction of Improved Catalysts for Nickel-Catalyzed Cross-Electrophile Coupling J. Am. Chem. Soc. 2024, 146, 3043–3051
70. Ryan, M. J.; Yang, N.; Kwac, K.; Wilhelm, K. B.; Chi, B. K.; Weix, D. J.; Cho, M.; Zanni, M. T. The hydrogen-bonding dynamics of water to a nitrile-functionalized electrode is modulated by voltage according to ultrafast 2D IR spectroscopy PNAS 2023, e2314998120
69. Twilton, J.†; Johnson, M. R.†; Sidana, V.; Franke, M. C.; Bottecchia, C.; Lehnherr, D.; Lévesque, F.; Knapp, S. M. M.; Wang, L.; Gerken, J. B.; Hong, C. M.; Vickery, T. P.; Weisel, M. D.; Strotman, N. A.; Weix, D. J.; Root, T. W.; Stahl, S. S. Quinone-mediated hydrogen anode for non-aqueous reductive electrosynthesis Nature 2023, 623, 71–76
68. Gilbert, M. M.; Trenerry, M. J.; Longley, V. R.; Castro, A. J.; Berry, J. F.; Weix, D. J. Ligand–Metal Cooperation Enables Net Ring-Opening C–C Activation/Difunctionalization of Cyclopropyl Ketones ACS Catalysis 2023, 13, 11277-11290
67. Akana-Schneider, B. D.; Weix, D. J. Reductive Arylation of Nitroarenes with Chloroarenes: Reducing Conditions Enable New Reactivity from Palladium Catalysts. J. Am. Chem. Soc. 2023, 145, 16150–16159
66. Mouat, J. M.; Widness, J. K.; Enny, D. G.; Meidenbauer, M. T.; Awan, F., Krauss, T. D.; Weix, D. J. CdS Quantum Dots for Metallaphotoredox-Enabled Cross-Electrophile Coupling of Aryl Halides with Alkyl Halides, ACS Catal. 2023, 13, 9018–9024
65. Wang, J.†; Ehehalt, L. E.†; Huang, Z.; Beleh, O. M.; Guzei, I. A.; Weix, D. J. Formation of C(sp2)–C(sp3) Bonds Instead of Amide C–N Bonds from Carboxylic Acid and Amine Substrate Pools by Decarbonylative Cross-Electrophile Coupling. J. Am. Chem. Soc. 2023, 145, 9951–9958.
64. Piszel, P. E.; Orzolek, B. J.; Olszewski, A. K.; Rotella, M. E.; Spiewak, A. M.; Kozlowski, M. C.; Weix, D. J. Protodemetalation of (Bipyridyl)Ni(II)–Aryl Complexes Shows Evidence for Five-, Six-, and Seven-Membered Cyclic Pathways. J. Am. Chem. Soc. 2023, 145, 8517–8528
63. Ackerman-Biegasiewicz, L. K. G.; Kariofillis S. K.; Weix, D. J.; Multimetallic-Catalyzed C–C Bond-Forming Reactions: From Serendipity to Strategy. J. Am. Chem. Soc. 2023, 145, 6596–6614.
62. Su, Z-M.; Twilton, J.; Hoyt, C. B.; Wang, F.; Stanley, L.; Mayes, H. B.; Kang, K.; Weix, D. J.; Beckham, G. T.; Stahl, S. S. Ni- and Ni/Pd-Catalyzed Reductive Coupling of Lignin-Derived Aromatics to Access Biobased Plasticizers. ACS Cent. Sci. 2023, 9, 159–165.
61. Franke, M. C.; Longley, V. R.; Rafiee, M.; Stahl, S. S.; Hansen, E. C.; Weix, D. J. Zinc-free, Scalable Reductive Cross-Electrophile Coupling Driven by Electrochemistry in an Undivided Cell. ACS Catal. 2022, 12, 12617–12626.
60. Salgueiro, D. C.†; Ehehalt, L. E.†; Johnson, K. A.; Weix, D. J. Discussion Addendum for: Nickel-Catalyzed Cross-Coupling of Aryl Halides with Alkyl Halides: Ethyl 4-(4-(4-methylphenylsulfonamido)-phenyl)butanoate. Org. Synth. 2022, 99, 215-233.
59. Widness, J. K.; Enny, D. G.; McFarlane-Connelly, K. S.; Miedenbauer, M. T.; Krauss, T. D.; Weix, D. J. CdS Quantum Dots as Potent Photoreductants for Organic Chemistry Enabled by Auger Processes. J. Am. Chem. Soc. 2022, 144, 12229–12246.
58. Salgueiro, D. C.; Chi, B. K.; Guzei, I. A.; García-Reynaga, P.; Weix, D. J. Control of Redox-Active Ester Reactivity Enables a General Cross-Electrophile Approach to Access Arylated Strained Rings. Angew. Chem. Int. Ed. 2022, 61, e202205673.
57. Kang, K.; Weix, D. J. Nickel-Catalyzed C(sp3)–C(sp3) Cross-Electrophile Coupling of In Situ Generated NHP Esters with Unactivated Alkyl Bromides. Org. Lett. 2022, 24, 2853–2857.
56. Chi, B. K.; Widness, J. K.; Gilbert, M. M.; Salgueiro, D. C.; Garcia, K. J.; Weix, D. J. In-Situ Bromination Enables Formal Cross-Electrophile Coupling of Alcohols with Aryl and Alkenyl Halides. ACS Catal. 2022, 12, 580–586.
55. Kang, K.; Loud, N. L.; DiBenedetto, T. A.; Weix, D. J. A General, Multimetallic Cross-Ullmann Biheteroaryl Synthesis from Heteroaryl Halides and Heteroaryl Triflates. J. Am. Chem. Soc. 2021, 143, 21484–21491.
54. Gilbert, M. M.; Weix, D. J. Mastering mono-bond metathesis. Nat. Chem. 2021, 13, 818–820.
53. Aguirre, A. L.; Loud, N. L.; Johnson, K. A.; Weix, D. J.; Wang, Y. ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand. Chem. Eur. J. 2021, 27, 12981-12986.
52. Kim, D.; Chen, C.; Mercado, B. Q.; Weix, D. J.; Holland, P. L. Mechanistic Study of Alkene Hydrosilylation Catalyzed by a β-Dialdiminate Cobalt(I) Complex. Organometallics 2020, 39, 2415-2424.
51. Kang, K.; Huang, L.; Weix, D. J. Sulfonate Versus Sulfonate: Nickel and Palladium Multimetallic Cross-Electrophile Coupling of Aryl Triflates with Aryl Tosylates. J. Am. Chem. Soc. 2020, 142, 10634-10640.
50. Kim, S.; Goldfogel, M. J.; Gilbert, M. M.; Weix, D. J. Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Chlorides with Primary Alkyl Chlorides. J. Am. Chem. Soc. 2020, 142, 9902-9907.
49. Wang, J.; Hoerrner, M. E.; Watson, M. P.; Weix, D. J. Nickel‐Catalyzed Synthesis of Dialkyl Ketones from the Coupling of N‐Alkyl Pyridinium Salts with Activated Carboxylic Acids. Angew. Chem. Int. Ed. 2020, 59, 13484-13489.
48. Goldfogel, M. J.; Huang, L.; Weix, D. J. Cross-Electrophile Coupling: Principles and New Reactions. In Nickel Catalysis in Synthesis: Methods and Reactions; Ogoshi, S., Ed.; Wiley-VCH: Weinheim, 2020, 352.
47. Spiewak, A. M.; Weix, D. J. Ruthenium-Catalyzed C-H Arylation of 1-Naphthol with Aryl and Heteroaryl Halides. J. Org. Chem. 2019, 84, 15642-15647.
46. Perkins, R. J.; Hughes, A. J.; Weix, D. J.; Hansen, E. C. Metal-Reductant-Free Electrochemical Nickel-Catalyzed Couplings of Aryl and Alkyl Bromides in Acetonitrile. Org. Process Res. Dev. 2019, 23, 1746-1751.
45. Wang, J.; Cary, B. P.; Beyer, P. D.; Gellman, S. H.; Weix, D. J. Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters. Angew. Chem. Int. Ed. 2019, 58, 12081-12085.
44. Huang, L.; Ackerman, L. K. G.; Kang, K.; Parsons, A. M.; Weix, D. J. LiCl-Accelerated Multimetallic Cross-Coupling of Aryl Chlorides with Aryl Triflates. J. Am. Chem. Soc. 2019, 141, 10978-10983.
43. Johnson, K. A.; Weix, D. J. When Two Metal Atoms are Better Than One. Science 2019, 363, 819.
42. Garcia, K. J.; Gilbert, M. M.; Weix, D. J. Nickel-Catalyzed Addition of Aryl Bromides to Aldehydes To Form Hindered Secondary Alcohols. J. Am. Chem. Soc. 2019, 141, 1823-1827.
41. Olivares, A. M.; Weix, D. J. Multimetallic Ni- and Pd-Catalyzed Cross-Electrophile Coupling To Form Highly Substituted 1,3-Dienes. J. Am. Chem. Soc. 2018, 140, 2446-2449.
40. Huihui, K. M. M.; Shrestha, R.; Weix, D. J. Nickel-Catalyzed Reductive Conjugate Addition of Primary Alkyl Bromides to Enones To Form Silyl Enol Ethers. Org. Lett. 2017, 19, 340-343.
39. Huang, L.; Olivares, A. M.; Weix, D. J. Reductive Decarboxylative Alkynylation of N-Hydroxyphthalimide Esters with Bromoalkynes. Angew. Chem. Int. Ed. 2017, 56, 11901-11905.
38. Caputo, J. A.; Frenette, L. C.; Zhao, N.; Sowers, K. L.; Krauss, T. D.; Weix, D. J. General and Efficient C-C Bond Forming Photoredox Catalysis with Semiconductor Quantum Dots. J. Am. Chem. Soc. 2017, 139, 4250-4253.
37. Batesky, D. C.; Goldfogel, M. J.; Weix, D. J. Removal of Triphenylphosphine Oxide by Precipitation with Zinc Chloride in Polar Solvents. J. Org. Chem. 2017, 82, 9931-9936.
36. Hansen, E. C.; Li, C.; Yang, S.; Pedro, D.; Weix, D. J. Coupling of Challenging Heteroaryl Halides with Alkyl Halides via Nickel-Catalyzed Cross-Electrophile Coupling. J. Org. Chem. 2017, 82, 7085-7089.
35. Wotal, A. C.; Batesky, D. C.; Weix, D. J. Nickel-Catalyzed Synthesis of Ketones from Alkyl Halides and Acid Chlorides: Preparation of Ethyl 4-Oxododecanoate. Org. Syn. 2016, 93, 50-62.
34. Johnson, K. A.; Biswas, S.; Weix, D. J. Cross-Electrophile Coupling of Vinyl Halides with Alkyl Halides. Chem. Eur. J. 2016, 22, 7399-7402.
33. Huihui, K. M. M.; Caputo, J. A.; Melchor, Z.; Olivares, A. M.; Spiewak, A. M.; Johnson, K. A.; DiBenedetto, T. A.; Kim, S.; Ackerman, L. K. G.; Weix, D. J. Decarboxylative Cross-Electrophile Coupling of N-Hydroxyphthalimide Esters with Aryl Iodides. J. Am. Chem. Soc. 2016, 138, 5016-5019.
32. Huang, L. B.; Weix, D. J. Ruthenium-Catalyzed C-H Arylation of Diverse Aryl Carboxylic Acids with Aryl and Heteroaryl Halides. Org. Lett. 2016, 18, 5432-5435.
31. Hansen, E. C.; Pedro, D. J.; Wotal, A. C.; Gower, N. J.; Nelson, J. D.; Caron, S.; Weix, D. J. New ligands for nickel catalysis from diverse pharmaceutical heterocycle libraries. Nat. Chem. 2016, 8, 1126-1130.
30. Anka-Lufford, L. L.; Huihui, K. M. M.; Gower, N. J.; Ackerman, L. K. G.; Weix, D. J. Nickel-Catalyzed Cross-Electrophile Coupling with Organic Reductants in Non-Amide Solvents. Chem-Eur J 2016, 22, 11564-11567.
29. Zhao, Y.; Weix, D. J. Enantioselective Cross-Coupling of meso-Epoxides with Aryl Halides. J. Am. Chem. Soc. 2015, 137, 3237-3240.
28. Weix, D. J. Methods and Mechanisms for Cross-Electrophile Coupling of Csp2 Halides with Alkyl Electrophiles. Acc. Chem. Res. 2015, 48, 1767-1775.
27. Dorn, S. C. M.; Olsen, A. K.; Kelemen, R. E.; Shrestha, R.; Weix, D. J. Nickel-catalyzed reductive arylation of activated alkynes with aryl iodides. Tetrahedron Lett. 2015, 56, 3365-3367.
26. Chen, C.; Hecht, M. B.; Kavara, A.; Brennessel, W. W.; Mercado, B. Q.; Weix, D. J.; Holland, P. L. Rapid, Regioconvergent, Solvent-Free Alkene Hydrosilylation with a Cobalt Catalyst. J. Am. Chem. Soc. 2015, 137, 13244-13247.
25. Caputo, J. A.; Naodovic, M.; Weix, D. J. Nickel-Catalyzed Allylation of α-Amido Sulfones To Form Protected Homoallylic Amines. Synlett 2015, 26, 323-326.
24. Ackerman, L. K. G.; Lovell, M. M.; Weix, D. J. Multimetallic catalysed cross-coupling of aryl bromides with aryl triflates. Nature 2015, 524, 454-457.
23. Ackerman, L. K. G.; Anka-Lufford, L. L.; Naodovic, M.; Weix, D. J. Cobalt co-catalysis for cross-electrophile coupling: diarylmethanes from benzyl mesylates and aryl halides. Chem. Sci. 2015, 6, 1115-1119.
22. Zhao, Y.; Weix, D. J. Nickel-catalyzed regiodivergent opening of epoxides with aryl halides: co-catalysis controls regioselectivity. J. Am. Chem. Soc. 2014, 136, 48-51.
21. Wotal, A. C.; Ribson, R. D.; Weix, D. J. Stoichiometric Reactions of Acylnickel(II) Complexes with Electrophiles and the Catalytic Synthesis of Ketones. Organometallics 2014, 33, 5874-5881.
20. Weix, D. J.; Kelemen, R. E.; Ackerman, L. K. G. Tandem catalysis. Access Science 2014
19. Robo, M. T.; Prinsell, M. R.; Weix, D. J. 4,4′,4″-Trimethyl-2,2′:6′,2″-terpyridine by Oxidative Coupling of 4-Picoline. J. Org. Chem. 2014, 79, 10624-10628.
18. Humes, C. L.; Banker, T. J.; Dorn, S. C. M.; Shanahan, J. P.; Brennessel, W. W.; Weix, D. J. Bis{(R)-N-[(R)-2-benzyloxy-1-(4-tert-butylphenyl)ethyl]-2-methylpropane-2-sulfinamide} monohydrate. Acta Crystallographica Section E 2014, 70, o405-o406.
17. Everson, D. A.; Weix, D. J. Cross-electrophile coupling: principles of reactivity and selectivity. J. Org. Chem. 2014, 79, 4793-8.
16. Everson, D. A.; Buonomo, J. A.; Weix, D. J. Nickel-catalyzed cross-electrophile coupling of 2-chloropyridines with alkyl bromides. Synlett 2014, 25, 233-238.
15. Chen, C.; Dugan, T. R.; Brennessel, W. W.; Weix, D. J.; Holland, P. L. Z-Selective Alkene Isomerization by High-Spin Cobalt(II) Complexes. J. Am. Chem. Soc. 2014, 136, 945-955.
14. Carbone, M. R.; Centola, G. A.; Haas, A.; McClelland, K. P.; Moskowitz, M. D.; Verderame, A. M.; Olezeski, M. S.; Papa, L. J.; Dorn, S. C. M.; Brennessel, W. W.; Weix, D. J. Crystal structures of (RS)-N-[(1R,2S)-2-benzyloxy-1-(2,6-dimethylphenyl)propyl]-2-methylpropane-2-sulfinamide and (RS)-N-[(1S,2R)-2-benzyloxy-1-(2,4,6-trimethylphenyl)propyl]-2-methylpropane-2-sulfinamide: two related protected 1,2-amino alcohols. Acta Crystallographica Section E 2014, 70, 365-369.
13. Buonomo, J. A.; Everson, D. A.; Weix, D. J. Substituted 2,2′-Bipyridines by Nickel Catalysis: 4,4′-Di-tert-butyl-2,2′-bipyridine. Synthesis 2013, 45, 3099-3102.
12. Shrestha, R.; Dorn, S. C.; Weix, D. J. Nickel-catalyzed reductive conjugate addition to enones via allylnickel intermediates. J. Am. Chem. Soc. 2013, 135, 751-62.
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8. Everson, D. A.; Jones, B. A.; Weix, D. J. Replacing conventional carbon nucleophiles with electrophiles: nickel-catalyzed reductive alkylation of aryl bromides and chlorides. J. Am. Chem. Soc. 2012, 134, 6146-59.
7. Anka-Lufford, L. L.; Prinsell, M. R.; Weix, D. J. Selective cross-coupling of organic halides with allylic acetates. J. Org. Chem. 2012, 77, 9989-10000.
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3. Shrestha, R.; Brennessel, W. W.; Weix, D. J. [2,2′-Bis(diphenylphosphanyl)-1,1′-binaphthyl-[κ]2P,P’]chlorido(4-methylphenylsulfonyl-[κ]S)palladium(II) dichloromethane trisolvate monohydrate. Acta Crystallographica Section E 2011, 67, m1830.
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